General Information

  • ID:  hor003709
  • Uniprot ID:  P84354
  • Protein name:  Periviscerokinin-1
  • Gene name:  NA
  • Organism:  Musca domestica (House fly)
  • Family:  Periviscerokinin family
  • Source:  animal
  • Expression:  Dorsal ganglionic sheath of fused ventral nerve cord.
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Musca (subgenus), Musca (genus), Muscini (tribe), Muscinae (subfamily), Muscidae (family), Muscoidea (superfamily), Calyptratae, Schizophora, Cyclorrhapha, Eremoneura, Muscomorpha (infraorder), Brachycera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  AGGTSGLYAFPRV
  • Length:  13
  • Propeptide:  AGGTSGLYAFPRV
  • Signal peptide:  NA
  • Modification:  T13 Valine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003709_AF2.pdbhor003709_ESM.pdb

Physical Information

Mass: 150968 Formula: C59H90N16O17
Absent amino acids: CDEHIKMNQW Common amino acids: G
pI: 9.35 Basic residues: 1
Polar residues: 6 Hydrophobic residues: 5
Hydrophobicity: 33.08 Boman Index: -265
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 67.69
Instability Index: 3942.31 Extinction Coefficient cystines: 1490
Absorbance 280nm: 124.17

Literature

  • PubMed ID:  14706527
  • Title:  Mass Spectrometric Analysis of Putative Capa-Gene Products in Musca Domestica and Neobellieria Bullata